A Study of the Metabolism of Calcium, Magnesium, Sulphur, Phosphorus, and Nitrogen in Acromegaly

A distinct retention of calcium, magnesium, and phosphorus was noted, which was not accompanied by corresponding changes in general metabolism, as evidenced by a practical balance of nitrogen and sulphur. It is concluded that there is a primary disturbance in the metabolism of the mineral elements mentioned, with the probable formation of new bony tissue. The distribution of elements between urine and feces shows no abnormal variations. A suggestion is made as to the reasons for variable calcium output in the urine on a uniform diet.